A Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986278 in Participants With Idiopathic Pulmonary Fibrosis

Inclusion Criteria

1. Subjects with IPF aged ≥ 40 years at the time of signing the informed consent.
2. Diagnosis of IPF within 7 years prior to screening that is supported by centrally read chest high-resolution computed tomography (HRCT) obtained at screening and verification of usual interstitial pneumonia.
3. If on pirfenidone or nintedanib, participants must have been on a stable dose for at least 90 days prior to screening.
4. If not currently on pirfenidone or nintedanib, participants must not have received either of these medications within 28 days prior to screening.
5. Women who are of childbearing potential must have a highly effective form of contraception and must provide a negative urine/serum pregnancy test.
6. Men who are sexually active with women of childbearing potential agree to use male barrier contraception.

Exclusion Criteria

1. History of stroke or transient ischemic attack within 3 months prior to screening.
2. Participants who exhibit symptoms of heart failure at rest.
3. Participants who have a current malignancy or a previous malignancy in the past 5 years prior to screening, except for those who have a documented history of cured nonmetastatic squamous cell skin carcinoma, basal cell skin carcinoma, or cervical carcinoma in situ.

* Other protocol-defined Inclusion/Exclusion criteria apply.